Appeal 2007-2254
Application 10/383,115
tetracycline compound” (Specification 2). Examples of tetracycline
compounds include doxycycline and minocycline (id. at 3).
The Specification states that the “maximal dosage [of the tetracycline
compound] for a subject is the highest dosage, which does not cause
undesirable or intolerable side effects” (id. at 5). The Specification
contemplates “doses from about 0.1 mg/kg/day to about 45 mg/kg/day, and
suitably, from about 1 mg/kg/day to about 18 mg/kg/day” (id.).
DISCUSSION
1. CLAIMS
Claims 1-3, 7, 9, 14, 15, 17, 20, 21, 30, 31, 47, and 48 are pending and
on appeal. The claims have not been argued separately and therefore stand
or fall together. 37 C.F.R. § 41.37(c)(1)(vii). We will focus on claim 1,
which is representative and reads as follows:
1. A method of treating Alzheimers’ disease comprising administering to
a mammal in need thereof a tetracycline compound formula (I)
2
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