Ex Parte Duncan - Page 6

                Appeal 2007-2254                                                                                 
                Application 10/383,115                                                                           

                skill in the art with a reasonable expectation of success in treating                            
                Alzheimer’s disease with tetracycline compounds, such as the ones recited in                     
                claim 1.  “Obviousness does not require absolute predictability of success.”                     
                In re O’Farrell, 853 F.2d 894, 903-04, 7 USPQ2d 1673, 1681 (Fed. Cir.                            
                1988).                                                                                           
                                                 SUMMARY                                                         
                       We conclude that the Examiner has set forth a prima facie case that                       
                claim 1 would have been obvious over Amin and Yrjanheikki in view of                             
                LeBlanc, which Appellant has not rebutted.  We therefore affirm the                              
                rejection of claim 1 under 35 U.S.C. § 103.  Claims 2, 3, 7, 9, 14, 15, 17, 20,                  
                21, 30, 31, 47, and 48 fall with claim 1.                                                        
                       No time period for taking any subsequent action in connection with                        
                this appeal may be extended under 37 C.F.R. § 1.136(a).                                          

                                                 AFFIRMED                                                        















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