Ex Parte Muller et al - Page 9

                  Appeal 2007-2524                                                                                         
                  Application 10/194,834                                                                                   
                         As noted above, claim 1 is not the only broad disclosure of a                                     
                  composition comprising ciprofloxacin.  Cagle discusses prior art (Cagle at                               
                  col. 1, ll. 48-53; FF 15) and its own compositions that comprise                                         
                  ciprofloxacin without preservatives (FF 6), including a specific example of                              
                  ciprofloxacin composition which lacks a preservative (Cagle at col. 8, l. 18;                            
                  FF 9-10).  Appellants have not provided any evidence that would contravene                               
                  Cagle’s explicit disclosure – including claim 1 and Example 2 – of                                       
                  ciprofloxacin compositions which lack preservative.                                                      
                         Appellants also contend that Cagle’s specification does not support                               
                  the “negative limitation . . . ‘free of any other component effective as a                               
                  preservative’ [because it] requires basis in the specification, and a failure of                         
                  the specification to contain such basis constitutes a violation of the written                           
                  description requirement for any claim containing a negative limitation” (                                
                  Reply Br. 5).  We do not see the relevance of this argument.  Cagle’s claim                              
                  does not recite a negative limitation.  The Examiner’s position, which we                                
                  find no error with, is that Cagle’s claim 1, in reciting a composition                                   
                  “comprising” ciprofloxacin, covers compositions both with and without                                    
                  BAC.                                                                                                     
                         For the foregoing reasons, we conclude that the Examiner did not err                              
                  in rejecting claims 36 as anticipated by Cagle.  Claims 37-43 falls with claim                           
                  36 because they were not separately argued.                                                              








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