Ex Parte Muller et al - Page 10

                  Appeal 2007-2524                                                                                         
                  Application 10/194,834                                                                                   
                  Claims 44-50                                                                                             
                         Claim 44 depends on claim 36, but is directed to a method of                                      
                  “administering to a living mammalian eye a therapeutically effective amount                              
                  of the composition of claim 36.”                                                                         
                         Appellants argue, as they did for claim 36, that “Cagle does not                                  
                  disclose administering to a living mammalian eye a therapeutically effective                             
                  amount of a self-preserved quinolone composition.  Rather, Cagle discloses                               
                  methods of administering a sustained release antibiotic composition; in the                              
                  only two examples (Examples 1 and 3) in which the sustained release                                      
                  composition is actually enabled, the composition also contains a separate                                
                  BAC preservative” (Br. 13).   For the same reasons discussed above, we do                                
                  not find this argument persuasive.                                                                       
                         Appellants also contend that “Example 3 [2; sic] discloses a                                      
                  composition lacking BAC, the concentration of the quinolone recited therein                              
                  (0.03%) is below the dosage claimed in any of the present method claims.                                 
                  Further, Example 2 is drawn to an experimental quinolone composition (for                                
                  determining the corneal partition coefficient) rather than a therapeutic                                 
                  composition” (Br. 13).  We do not agree.  Example 2 is not cited as an                                   
                  anticipatory composition; rather Example 2 is evidence that a preservative is                            
                  not a necessary component of Cagle’s solution.                                                           
                         For the foregoing reasons, we conclude that the Examiner did not err                              
                  in rejecting claims 44 as anticipated by Cagle.  Claims 45-50 fall with claim                            
                  44 because they were not separately argued.                                                              





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