Ex Parte Goddard et al - Page 7

                Appeal 2007-2953                                                                              
                Application 10/175,749                                                                        

                recognized, as of this application’s effective filing date, to be an established              
                or promising treatment for such diseases.                                                     
                      Appellants have not disclosed any specific disorder that could be                       
                effectively treated with the claimed polypeptide or an inhibitor of it.                       
                Therefore, their argument that the claimed polypeptide “allows the                            
                development of novel therapies directed to the targeting and/or treatment of                  
                diseases involving protein misfolding and cellular viability/proliferation,                   
                such as various types of cancer,” does not persuade us that the identification                
                of SEQ ID NO:74 as a PDI-related protein is sufficient, in itself, to establish               
                the patentable utility of the claimed polypeptide.                                            
                                                SUMMARY                                                       
                      Appellants have not disclosed a specific and substantial utility for the                
                claimed polypeptide.  We therefore affirm the rejections of claims 25-32 and                  
                35-37 under 35 U.S.C. §§ 101 and 112, first paragraph, for lack of                            
                patentable utility.                                                                           
                      No time period for taking any subsequent action in connection with                      
                this appeal may be extended under 37 C.F.R. § 1.136(a)(1)(iv) (2006).                         
                                                AFFIRMED                                                      


                dm                                                                                            

                KNOBBE, MARTENS, OLSON & BEAR, LLP                                                            
                2040 MAIN STREET                                                                              
                IRVINE CA 92614                                                                               



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