Ex Parte Syverson et al - Page 3

               Appeal 2007-3216                                                                            
               Application 10/271,433                                                                      
               over Brown-Skrobot (U.S. Pat. No. 5,547,985, issued Aug. 20, 1996) in                       
               view of Mitra (U.S. Pat. No. 5,686,088, issued Nov. 11, 1997) (Answer 3).                   
                      We select claims 1 and 41 as representative of the appealed claims.                  
               Claims 1 and 41 read as follows:                                                            
                      1. A method of inhibiting the production of TSST-1 from Gram                         
                      positive bacteria located in and around the vagina of a woman,                       
                      the method comprising                                                                
                            exposing the Gram positive bacteria located in and                             
                      around the vagina of the woman to a liquid vaginal formulation                       
                      comprising a pharmaceutically acceptable carrier and an                              
                      effective amount of a first active ingredient selected from the                      
                      group consisting of hexachlorophene, benzylparaben, benzyl                           
                      salicylate, benzophenone-6, benzophenone-7, benzophenone-8,                          
                      benzophenone-9, benzophenone-10, benzophenone-12,                                    
                      benzophenone-1, benzophenone-2, benzophenone-3,                                      
                      chlorophene, 2,4-diaminodiphenylamine, dichlorophene, HC                             
                      Green No. 1, HC Orange No. 1, HC Red No. 1,                                          
                      isopropylbenzylsalicylate, and phenyl salicylate, wherein the                        
                      vaginal formulation is suitable for use in a woman’s vagina.                         
                      41. The method as set forth in claim 1 wherein the first active                      
                      ingredient is present in an amount of about 2.5 x 10-4% (w/w).                       

                                          FINDINGS OF FACT                                                 
               Brown-Skrobot                                                                               
               B1.  According to Brown-Skrobot, “many women use liquid vaginal                             
               douches to irrigate and cleanse the vagina and prevent vaginal infections”                  
               (Brown-Skrobot, at col. 1, ll. 25-27).  Several prior art compositions are                  
               described by Brown-Skrobot, including compositions that contain                             
               germicidal surfactants (Brown-Skrobot, at col. 1, ll. 38-60).                               




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