Ex Parte Liu et al - Page 6

                Appeal 2007-3390                                                                             
                Application 10/143,915                                                                       
                      As discussed above, the device used in Kim’s method for transdermal                    
                administration of vitamin C utilizes both electrical potential energy                        
                (iontophoresis) and ultrasonic waves (sonophoresis).  Claim 4 does not                       
                exclude this combination.  Accordingly, we are not persuaded by                              
                Appellants’ assertion that Kim “only teaches applying a vitamin C                            
                composition to the skin, and enhancing its penetration with iontophoresis”                   
                (Br. 6).                                                                                     
                      While Appellants recognize that “the Examiner is correct that Spencer                  
                teaches that sonophoresis is known to be similarly useful as iontophoresis,                  
                Appellant[s] respectfully disagree[] that there is any suggestion in Spencer,                
                Kim et al., or any other prior art of record for substituting the sonophoresis               
                teaching of Spencer into the iontophoresis teachings of Kim et al.” (Br. 6.)                 
                We find, however, that a substitution of sonophoresis for iontophoresis is not               
                required in this instance.  On this record, the Examiner has established that                
                iontophoresis and sonophoresis are both known to enhance the skin’s                          
                absorption of topical actives (Answer 4).  Appellants agree with this finding                
                (Br. 6).  In this regard, the Examiner relies on Kim, which teaches a method                 
                for transdermal administration of vitamin C that utilizes both iontophoresis                 
                and sonophoresis.  Accordingly, no modification of Kim’s method or device                    
                is necessary.  See KSR Int’l Co. v. Teleflex Inc., 127 S. Ct. 1727, 1741, 82                 
                USPQ2d 1385, 1397 (2007) (“In determining whether the subject matter of a                    
                patent claim is obvious, neither the particular motivation nor the avowed                    
                purpose of the patentee controls.  What matters is the objective reach of the                
                claim.  If the claim extends to what is obvious, it is invalid under § 103.”)                
                Therefore, we are not persuaded by Appellants’ argument to the contrary.                     



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