Appeal No. 95-2603
Application 07/915,871
2,6'-bis-1,4,8,11-tetraazacyclotetradecane
11,11'-(1,2-ethanediyl)bis-1,4,8,11-tetraazacyclotetradecane
11,11'-(1,2-propanediyl)bis-1,4,8,11-tetraazacyclotetradecane
11,11'-(1,2-butanediyl)bis-1,4,8,11-tetraazacyclotetradecane
11,11'-(1,2-pentanediyl)bis-1,4,8,11-tetraazacyclotetradecane
11,11'-(1,2-hexanediyl)bis-1,4,8,11-tetraazacyclotetradecane
and a pharmaceutically acceptable carrier therefor.
7. A composition as claimed in claim 23, wherein
the active ingredient is 2,2'-bicyclam.
8. A composition as claimed in claim 23, wherein
the active ingredient is 6,6'-bicyclam.
The references relied upon by the examiner as evidence of
obviousness are:
Lehn 4,156,683 May 29,
1979
Zimenkovskii et al. (Zimenkovskii), Chemical Abstracts (CA),
Vol. 88, No. 15, No. 105292s (1978)
Williams et al. (Williams), CA, Vol. 96, No. 97239c (1981)
Kimura et al. (Kimura), CA, Vol. 99, No. 49518h (1983)
Rowatt et al. (Rowatt), CA, Vol. 107, No. 112499d (1987)
Ciampolini et al. (Ciampolini), CA, Vol. 107, No. 167695v
3
Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Next
Last modified: November 3, 2007