Ex parte MURRER et al. - Page 12




                                                 Appeal No. 95-2603                                                                                                                                                                                                                                                                                                                                                                    
                                                 Application 07/915,871                                                                                                                                                                                                                                                                                                                                                                


                                                 by appellants does not appear to have any substituent group at                                                                                                                                                                                                                                                                                                                        
                                                 the 1- or 1'-positions of the tetraazacyclotetradecane groups.                                                                                                                                                                                                                                                                                                                        
                                                 Hence, the compound 11,11'-(1,2-ethanediyl)bis-1,4,8,11-                                                                                                                                                                                                                                                                                                                              
                                                 tetraazacyclotetradecane could as easily have been, and                                                                                                                                                                                                                                                                                                                               
                                                 normally would have been, identified as 1,1'-(1,2-                                                                                                                                                                                                                                                                                                                                    
                                                 ethanediyl)bis-1,4,8,11-tetraazacyclotetradecane, as is                                                                                                                                                                                                                                                                                                                               
                                                 readily apparent by comparing the following chemical                                                                                                                                                                                                                                                                                                                                  
                                                 structures:                                                                                                                                                                                                                                                                                                                                                                           


                                                 +)))))))))))))))))))))))))))))))))))))))))))))))))))))))),                                                                                                                                                                                                                                                                                                                            
                                                 *                                                        *                                                                                                                                                                                                                                                                                                                            
                                                 *  1   2   3  4  5   6  7   8   9  10  11  12 13  14     *                                                                                                                                                                                                                                                                                                                            
                                                 .))N)))CH )CH )NH)CH )CH )CH )NH))CH )CH )NH))CH )CH )CH ))))-                                                                                                                                                                                                                                                                                                                        
                                                                               2             2                       2             2            2                         2            2                        2             2             2                                                                                                                                                                                          
                                                 *                                                                                                                                                                                                                                                                                                                                                                                     
                                                 CH2                                                                                                                                                                                                                                                                                                                                                                                   
                                                 *                                                                                                                                                                                                                                                                                                                                                                                     
                                                 CH2                                                                                                                                                                                                                                                                                                                                                                                   
                                                 *                                                                                                                                                                                                                                                                                                                                                                                     
                                                 +))N)))CH )CH )NH)CH )CH )CH )NH))CH )CH )NH))CH )CH )CH )))),                                                                                                                                                                                                                                                                                                                        
                                                                               2             2                       2             2            2                         2            2                        2             2             2                                                                                                                                                                                          
                                                 *  1'  2'  3' 4' 5'  6' 7'  8'  9' 10' 11' 12'13' 14'    *                                                                                                                                                                                                                                                                                                                            
                                                 *                                                        *                                                                                                                                                                                                                                                                                                                            
                                                 .))))))))))))))))))))))))))))))))))))))))))))))))))))))))-                                                                                                                                                                                                                                                                                                                            
                                                                                                       1,1'-(1,2-ethanediyl)bis-1,4,8,11-tetraazacyclotetradecane                                                                                                                                                                                                                                                                      
                                                                                                                                                                   (when viewed from the top)                                                                                                                                                                                                                                          
                                                 and                                                                                                                                                                                                                                                                                                                                                                                   





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