Ex parte MURRER et al. - Page 9




                     Appeal No. 95-2603                                                                                                                                                
                     Application 07/915,871                                                                                                                                            


                     fails to point out where the reference discloses the bis                                                                                                          
                     compounds of the claimed compositions.  Kimura is directed to                                                                                                     
                     the study of macrocyclic complexes and their effects on                                                                                                           
                     superoxide dismutase activities.  Thus there is no suggestion                                                                                                     
                     to combine this reference with Lehn and, even if properly                                                                                                         
                     combined, these references would not suggest the composition                                                                                                      
                     of the appealed claims.  See In re Bond, 910 F.2d 831, 834, 15                                                                                                    
                     USPQ2d 1566, 1568 (Fed. Cir. 1990).                                                                                                                               
                                Ciampolini, as characterized by the examiner, teaches the                                                                                              
                     11, 11'-positional isomer of one of the active ingredients in                                                                                                     
                     claim 23, along with its combination with various carriers                                                                                                        
                     (answer, page 8).  The examiner concludes that “it is well                                                                                                        
                     settled patent law that positional isomers would have been                                                                                                        
                                                                                        6                                              7                                              
                     obvious to the skilled artisan” , citing In re Wilder.                                                                                                            
                     Appellants argue that the examiner has misidentified the                                                                                                          
                     disclosed bicyclic compound of Ciampolini but, regardless,                                                                                                        


                                6    The examiner incorrectly includes the active ingredients of dependent claims 7                                                                    
                     and 8 as positional isomers of the compounds disclosed by Ciampolini (answer, page 8).                                                                            
                     The compounds recited in dependent claims 7 and 8 are bicyclam isomers which contain no                                                                           
                     bridging group, i.e., no 1,2-ethanediyl group.                                                                                                                    

                                7  563 F.2d 457, 195 USPQ 426 (CCPA 1977).                                                                                                             
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