Appeal No. 95-0885
Application 07/725,327
where n is 1-4, and where R is hydrogen of lower alkyl or 1-4 carbons and the
31
cyclohexane ring may be optionally substituted at any available methylene with
single oxo or hydroxy.
18. The method of claim 1 wherein the thiazolidine derivative is 5-{4-[2-(5-
ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidine dione.
The Prior Art
The following prior art reference is relied upon by the examiner in support of the rejection of
obviousness:
Hindley 5,002,953 Mar. 26, 1991
(parent filed Aug. 30, 1988)
Hindley discloses a substituted-thiazolidinedione derivative. The patentee discloses the following at
col. 1, lines 19-29:
It has now surprisingly been discovered that certain novel substituted-
thiazolidinedione derivatives show improved blood-glucose lowering activity and are
therefore of potential use in the treatment and/or prophylaxis of hyperglycaemia and
are of particular use in the treatment of Type II diabetes.
-3-
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