Ex parte PERSHADSINGH et al. - Page 11




                   Appeal No. 95-0885                                                                                                                                  
                   Application 07/725,327                                                                                                                              


                   that Hindley’s compounds and derivatives would alleviate essential hypertension.  We find no                                                        
                   evidence of record which would rebut the prima facie case.  In re Hedges, 783 F.2d 1038, 1041, 228                                                  
                   USPQ 685, 687 (Fed. Cir. 1986); In re Piasecki, 745 F.2d 1468, 1471-1473,  223 USPQ 785, 787-                                                       
                   788  (Fed. Cir. 1984).                                                                                                                              








                                                                           Conclusion                                                                                  
                   For the reasons given above, the rejection of claims 1-7 and 9-17 for obviousness over Hindley  is                                                  
                   affirmed while the rejection of claim 18 over Hindley is reversed.   Accordingly, the decision of the                                               
                   examiner is affirmed-in-part.                                                                                                                       
                                                                   AFFIRMED-IN-PART                                                                                    










                                                           JOHN D. SMITH                        )                                                                      
                                                          Administrative Patent Judge       )                                                                         
                                                                                                 )                                                                    
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