Appeal No. 94-4265
Application 08/035,915
wherein R can be a hydroxyalkyl group, R can be an alkoxycarbonyl group, R can be a C -C11 12 13 1 4
14 15
alkyl group or aryl group, R can be a C -C alkylthio group, R can be a lower alkoxy group, X
1 4
is a halogen atom or a reactive ester residue, and COOR is a protected carboxyl group (EP 45198:
p. 2, line 4 to p. 3, line 1; p. 5, lines 8-29; p. 10, line 24 to p. 11, line 4; p.18, line 24 to p. 19, line 3).
The reaction mechanism in EP 45198 is similar to appellants’ claimed mechanism, the
principle differences being substituent R at the 1-position of the penem structure and the starting12
compound (formula (IX)) for the reaction. While appellants’ R and R in EP 45198 can be a C -C3 13 1 4
2 12
alkyl group or phenyl, appellants’ R and R in EP 45198 are different. Appellants’ compound
2 12
defines R as being hydrogen, a C -C alkyl group or a phenyl group while EP 45198 defines R as
1 8
being, for example, a C -C alkoxycarbonyl group or a C -C alkylcarbonyl (EP 45198: p. 5, lines1 4 1 4
-8-
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Last modified: November 3, 2007