Ex parte BOUFFARD et al. - Page 13




          Appeal No. 95-3387                                                          
          Application No. 08/005,942                                                  


                    exert herbicidal action" and characterizing                       
                    this as a use in a "minor capacity" (emphasis                     
                    added) to "further support the rejection."                        
                    Appellant's complaint seems to be justified,                      
                    and if we did not find the rejections based                       
                    solely on Molotsky and the French patent to                       
                    be sound, we might well feel constrained to                       
                    reverse the decision of the board.  Where a                       
                    reference is relied on to support a rejection,                    
                    whether or not in a "minor capacity," there                       
                    would appear to be no excuse for not positively                   
                         including the reference in the statement of the              
                         rejection.                                                   
          We do not consider the Schwartz reference to have been cited                
          in the rejection before us, particularly since the examiner                 
          failed to indicate inclusion of the reference in the rejection              
          and specifically indicated on page 3 of the Examiner's Answer               
          that no “new prior art has been applied in this examiner's                  
          answer.”  Thus, we consider the issue of whether any of                     
          Schmatz, '310 Pat., '067 Pat. or Michel enable a method of                  
          making a compound which lacks a methyl at the fourth carbon of              
          the hydroxyproline residue of the hexapeptidyl compounds                    
          disclosed by the references.  Each of these references                      
          disclose obtaining the core cyclic hexapeptidyl compounds from              
          microbial fermentates.  In these references there is no                     
          discussion of culturing the exemplified microorganisms or                   
          other strains so as to obtain mixtures of cyclic hexapeptidyl               
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