Appeal No. 95-3387 Application No. 08/005,942 variants in echinocandin-containing fermentates of microorganisms of the species Zalerion arboricola, as well as methods of enriching the fermentate with respect to desmethyl variants and means of separating the variants from each other. While provisions exist for the presentation of such a rejection by this panel, we decline to make the necessary findings of fact in this case and consider that it is more prudent for the examiner to do so in the first instance. The examiner should conduct a claim-by-claim analysis of the differences between the claims and the prior art, should consider the level of skill of the ordinary artisan at the time of the invention and decide whether a prima facie case of obviousness exists. We also note the declarations of Dr. James Balkovec and Dr. Kenneth F. Bartizal, Jr. filed previously in this record as Paper Nos. 7 and 8, respectively. This evidence appears to be relevant and may well provide an adequate rebuttal, at least with respect to some of the claimed compounds, to any consideration as to whether the claimed compounds, compositions and method are obvious in view 15Page: Previous 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 NextLast modified: November 3, 2007