Ex parte BOUFFARD et al. - Page 15




          Appeal No. 95-3387                                                          
          Application No. 08/005,942                                                  


          variants in echinocandin-containing fermentates of                          
          microorganisms of the species Zalerion arboricola, as well as               
          methods of enriching the fermentate with respect to desmethyl               
          variants and means of separating the variants from each other.              
          While provisions exist for the presentation of such a                       
          rejection by this panel, we decline to make the necessary                   
          findings of fact in this case and consider that it is more                  
          prudent for the examiner to do so in the first instance.  The               
          examiner should conduct a claim-by-claim analysis of the                    
          differences between the claims and the prior art, should                    
          consider the level of skill of the ordinary artisan at the                  
          time of the invention and decide whether a prima facie case of              
          obviousness exists.  We also note the declarations of Dr.                   
          James Balkovec and Dr. Kenneth F. Bartizal, Jr. filed                       
          previously in this record as Paper Nos. 7 and 8, respectively.              
          This evidence appears to be relevant and may well provide an                
          adequate rebuttal, at least with respect to some of the                     
          claimed compounds, to any consideration as to whether the                   
          claimed compounds, compositions and method are obvious in view              




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