Ex parte RILEY et al. - Page 11




                 Appeal No. 95-1083                                                                                                                     
                 Application No. 08/004,444                                                                                                             
                 dismutase activity.  The examiner (Answer, page 9) found the evidence not persuasive                                                   
                 "since the superoxide dismutase activity of the instant compounds is clearly suggested by                                              
                 the prior art as discussed . . . .  ".   However, the examiner has pointed to no manganese                                             
                 complex of nitrogen containing sixteen-member macrocyclic ligands, within the scope of                                                 
                 the claimed subject matter, which have superoxide dismutase activity.  In addition, the                                                
                 examiner has offered no facts or evidence to rebut the evidence, presented by the                                                      
                 appellants, as to the unpredictability of substituting one transition metal for another in this                                        
                 type of complex.  Thus, on the                                                                                                         




                 record before us, we find that the examiner has failed to present facts or evidence which                                              
                 would support a prima facie case of unpatentabilty of the claimed subject matter.                                                      
                          The rejection of claims 1-3, 5-8, and 12 under 35 U.S.C. § 103 is reversed.                                                   
                                                                    SUMMARY                                                                             

                          To summarize, the decision of the examiner to reject claims 1-3, 5-8 and 12 under                                             
                 35 U.S.C. § 101 and 35 U.S.C. § 112, first paragraph is reversed.  The rejection of claims                                             
                 1-3, 6-8, and 12 under 35 U.S.C. § 103 is reversed.                                                                                    
                                                                   REVERSED                                                                             






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