Ex parte GHIONE et al. - Page 15


            Appeal No. 1995-3257                                                      
            Application 08/056,382                                                    



            claim that is directed to any use.  Since examiner has not questioned that the claimed
            monoclonal antibody does in fact work as an antidote to anthracycline antibiotics, it is unclear
            why examiner is questioning   the same antidotal effect in the particular context of preventing
            alopecia.                                                                 
                 Since examiner has not met the initial burden of providing reasons why a supporting
            disclosure does not enable the claims, we reverse the rejection.          
            Anticipation                                                              
                 Claims 6-9, 11, 19 and 20 are rejected under 35 U.S.C. ' 102(b) as being
            anticipated by Balsari I or II.                                           
                 AFor a prior art reference to anticipate in terms of                 
            35 U.S.C. ' 102, every element of the claimed invention                   
            must be identically shown in the single reference,@ In re                 
            Bond, 910 F.2d 831, 832, 15 USPQ2d 1566, 1567 (Fed. Cir.                  
            1990).  Since the prior art does not teach every element                  
            of the claimed invention, we reverse the rejection.                       
                 Setting aside whether the references teach the                       
            particular monoclonal antibody recited in the claims,                     
            they do not teach a composition comprising the  mAb at                    
            an "antidotal effective amount".  Examiner has not                        


            directed us to where in the references this is disclosed                  

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