Ex parte WOLDEMUSSIE et al. - Page 12




              Appeal No. 95-4823                                                                                             
              Application 07/856,012                                                                                         



              means that for Pino Capote’s purposes this parameter was only measured for 20 minutes.                         
              Second, claim 11 on appeal does not require any particular length of time for intraocular                      
              pressure to be reduced as a result of the claimed treatment.  Thus, a procedure which falls                    
              within the scope of claim 11 on appeal would not be outside the scope of claim 11 on                           
              appeal merely because that procedure resulted in reducing intraocular pressure for less                        
              than 20 minutes.                                                                                               
                      Appellants also criticize Pino Capote in that the reference does not purportedly                       
              describe an ophthalmic composition as required by claim 11 on appeal.  Appellants point                        
              out that Pino Capote describes a solution of diazepam and dimethylacetamide, which                             
              appellants assert is not suitable for administration into the eye for therapeutic purposes.                    
              Upon return of the application the examiner should determine whether the specific solution                     
              used by Pino Capote would reasonably be considered an “ophthalmic” solution.  In making                        
              this determination, the examiner should take into account that the cats treated in the                         
              reference were “decerebrated.”  If the specific solution used in the reference can not be                      
              reasonably described as “ophthalmic” the examiner should consider whether one of                               
              ordinary skill in the art would have found it obvious to formulate diazepam in an ophthalmic                   
              form in view of the successful results reported by Pino Capote.                                                





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