Ex parte ROSE et al. - Page 4




              Appeal No. 1995-4867                                                                                     
              Application 07/993,482                                                                                   


              examiner has discounted or dismissed this language in considering the patentability of                   
              claim 31.  As stated in the paragraph bridging pages 6-7 of the examiner's answer, “[f]irst,             
              it is important to note that appellants are claiming a compound (i.e., an expression                     
              cassette), not a method of secreting a polypeptide.  Such an intended use carries no                     
              patentable weight.”  We disagree with the examiner that this language recites only an                    
              intended use and carries “no patentable weight.”                                                         
                     It is axiomatic the claims are read in light of the supporting specification.  In re Zletz,       
              893 F.2d 319, 321-22, 13 USPQ2d 1320, 1322 (Fed. Cir. 1989); In re Moore,                                
              439 F.2d 1232, 1235, 169 USPQ 236, 238 (CCPA 1971).  As set forth at page 3, lines 7-                    
              13 of the specification, the expression cassettes of the present invention allow for                     
              secretion of a polypeptide.  As explained at page 18, lines 1-11 of the specification:                   
                            [w]here the product is retained in the host cell, the cells are harvested,                 
                     lysed and the product isolated and purified by extraction, precipitation,                         
                     chromatography, electrophoresis, and the like.  Where the product is                              
                     secreted into the periplasmic space, the cells are harvested and the product                      
                     is liberated by destruction of the cell wall, e.g., by hypotonic shock and the                    
                     like.  Where the product is secreted into the medium, the nutrient medium                         
                     may be collected and the product isolated by conventional means, for                              
                     example, affinity chromatography.”                                                                
                     As recognized by the examiner, the subject matter before us in this appeal is a                   
              compound.  As stated in In re Papesch, 315 F.2d 381, 391, 137 USPQ 43, 51 (CCPA                          
              1963), “From the standpoint of the patent law, a compound and all of its properties are                  
              inseparable; they are one and the same.”  Appellants describe a number embodiments of                    

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