Appeal No. 95-4914 Application No. 08/036,116 nanoparticles. See de Vringer at page 5, lines 13-21. Accordingly, we agree with the examiner that a prima facie case of obviousness is established for the subject matter defined by the broader claims on appeal. We also find that de Vringer fairly suggests the subject matter of the separately argued dependent claims. For example, appealed claim 2 specifies a mean droplet size range of between about 0.1 and 0.3 microns (i.e., between 100 and 300 nanometers) while de Vringer discloses a somewhat broader droplet size range between 50 and 1000 nanometers(page 4, line 35) and exemplifies a composition having a mean particle size droplet of 132 nanometers (page 6, line 12). With respect to the appealed claims 20 and 21, which call for a skin penetration enhancer component, we note that de Vringer also contemplates the use of penetration enhancers. See page 5, lines 25 and 26 of the reference. With respect to appellants’ arguments that imply that de Vringer does not suggest application of the prior art compositions to treat skin disorders, for example, as specified in appealed claim 25, we point out that de Vringer’s compositions are useful as anti- psoriatics and anti-eczema agents. See the reference at page 8Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007