Appeal No. 97-3292 Application 08/522,827 step of inserting an optic probe through a hollow tube, with the optic probe comprising, inter alia, an optic fiber bundle and a hollow needle, the optic fiber bundle disposed coaxially within the hollow needle, the hollow needle having a mirror for reflecting light transmitted to and from the optic fiber bundle at approximately a 90 degree angle relative to the longitudinal axis of the optic fiber bundle and having a window through which the reflected light may pass. We turn now to the evidence of obviousness. Alfano teaches an in-vivo spectroscopy diagnosis technique or method for distinguishing cancerous tissue from noncancerous tissue. As disclosed by the patentee (column 7, lines 44 through 47), instead of an endoscope 17 (Fig. 11), the probe may comprise an optical fiber bundle inside a needle for use in probing, i.e., penetrating directly inside a tissue such as the breast for direct optical biopsy. 5Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007