Appeal No. 97-3292 Application 08/522,827 The Shipp patent, for example, reveals the known practice relative to the use of a trocar wherein a blade (clearly suggestive of a solid needle) is removed from the trocar in order to allow surgical instruments to pass therethrough. We are in accord with the examiner’s view that the combined teachings of Alfano and Shipp or Wilk would have clearly been suggestive to one having ordinary skill in the art of inserting the probe disclosed by Alfano through a hollow tube previously inserted (with a solid needle subsequently removed) to obtain the expected advantage thereof. The Janes patent makes us aware that, at the time of appellants’ invention, it was a known practice in the art to follow an in-vivo optical diagnosis of tissue (system of Fig. 14 using a probe 268) with the removal of samples (column 2, lines 34 through 36 and column 6, lines 60 through 62). With this latter knowledge, it is clear to this panel of the board that one having ordinary skill in the art would have additionally found it obvious to take a sample subsequent to practicing the modified Alfano procedure, supra, for the self 6Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007