Ex parte ENGELSON et al. - Page 12




          Appeal No. 1999-0610                                      Page 12           
          Application No. 08/601,186                                                  


          of friction approximating that of silicone, for example, or                 
          lower.8                                                                     
               In rejecting claims 49 through 60 under 35 U.S.C. § 103,               
          the examiner relies upon the combined teachings of Castillo                 
          and Eury.  The examiner and appellants agree that Castillo                  
          discloses a catheter comprising a relatively flexible distal                
          segment (tip 14), a relatively stiff proximal segment                       
          (catheter body 15), carrying a reinforcing braid (column 3,                 
          lines 20-22) and a transition zone (13) which is free of the                
          reinforcing braid, and thus more flexible than the proximal                 
          segment, but less flexible than the distal segment (column 3,               
          lines 49-53).  The examiner concedes, however, that Castillo                
          does not disclose a coating on the distal segment of the                    
          catheter.                                                                   
               Eury discloses an antithrombogenic surface coating for                 
          use on biomedical devices, such as catheters, which come into               
          contact with a patient's blood flow, to present a blood                     
          contacting surface which is as hemocompatible as possible so                


               8This accords with the use of the term "lubricious" in the biomedical  
          field as exemplified by Sahatjian (column 1, lines 49 to 52, and column 2,  
          lines 32 to 35) and Whitbourne (column 1, lines 15 to 19).                  







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