Ex parte NICHOLSON - Page 5



          Appeal No. 1996-2229                                                        
          Application 08/196,748                                                      



          18 kDa as determined on silver stained SDS-polyacrylamide                   
          denaturing gel, and substantially free of other contaminants.               
          The claims do, in fact, set out and circumscribe a particular               
          area with a reasonable degree of precision and particularity.  In           
          re Moore,                                                                   
          439 F.2d 1232, 1235, 169 USPQ 236, 238 (CCPA 1971).                         


                                  35 U.S.C. §§ 102/103                                
               Claims 1 through 4 stand rejected under 35 U.S.C. § 102 as             
          anticipated by or, in the alternative, under 35 U.S.C. § 103 as             
          unpatentable over Söderström (U), Yoshimoto (RR), Yoshimoto (SS),           
          or Söderström (TT).  In entering these rejections, the examiner             
          does not designate any particular passage or passages relied on             
          in the cited references.  See 37 CFR § 1.104(c)(2), which states:           
                    In rejecting claims for want of novelty or for                    
                    obviousness, the examiner must cite the best                      
                    references at his or her command.  When a                         
                    reference is complex or shows or describes                        
                    inventions other than that claimed by the                         
                    applicant, the particular part relied on must                     
                    be designated as nearly as practicable. The                       
                    pertinence of each reference, if not apparent,                    
                    must be clearly explained and each rejected                       
                    claim specified. [emphasis added]                                 
          This the examiner has not done.  Nor does the appellant discuss             
          specific portions or passages of the cited references.  For this            

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