Appeal No. 1996-2229 Application 08/196,748 appropriate Office action setting forth the basis for that position. In so doing, the examiner should designate “as nearly as practicable” the particular part or passage of each prior art reference relied on. 37 CFR § 1.104(c)(2). Further, the examiner should provide a substantive response to appellant's reliance on Nicholson as evidence of non-obviousness. See the Appeal Brief, page 6. Further, in reevaluating the patentability of claims 1 through 4 on prior art grounds, the examiner should consider the proper interpretation of those claims as discussed in the first section of this opinion. We remand this application to the examiner to reevaluate the patentability of claims 1 through 4 in light of the foregoing discussion. On the surface, it would appear the Yoshimoto (RR) constitutes the closest prior art in this case. This follows from the examiner's argument that Yoshimoto (RR) describes a 91- fold purification of LTC synthase (Examiner's Answer, page 7) 4 and appellant's similar description of that reference in the Appeal Brief, page 5. Therefore, on return of this application, we recommend that the examiner pay particular attention to Yoshimoto (RR). The examiner should explain why the subject matter sought to patented in claims 1 through 4, properly 7Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007