Appeal No. 97-1843
Application 08/092,574
1,000 cps to 100,000 cps at 20EC. Kogyo discloses that the carboxyvinyl polymer can be
a CARBOPOL polymer. Kogyo, page 1, lines 40-54.
(2) Kogyo discloses that the carboxyvinyl polymer is used in the form of an aqueous
solution having a concentration of 0.05 to 5.0% by weight. Kogyo, page 2, lines 99-102.
(3) Kogyo discloses that the ophthalmic drug used in the gel compositions can be
insoluble or soluble in water. Kogyo, page 1, lines 87-89. Kogyo discloses that the
ophthalmic drug includes antibiotics. Kogyo, page 1, line 129, to page 2, line 3. Said
ophthalmic drug can be dissolved or dispersed in the aqueous carboxyvinyl polymer
solution. Kogyo, page 2, lines 11-15.
(4) Kogyo discloses that the gel compositions that have a viscosity of from 1,000 to
10,000 cps have good flowability. Said gel compositions can be applied as drops directly
on to the mucous membrane around the eyeball. Kogyo, page 2, lines 46-49.
(5) Kogyo discloses that when its ophthalmic gel compositions are applied, the
tears liquefy the gel to give a liquid which can be readily absorbed by the mucous
membrane and cornea. Kogyo, col. 2, lines 56-59. Kogyo discloses that conventional eye
lotions, which have a viscosity of less than 1,000 cps, are likely to be washed away by
tears. However, Kogyo also discloses that its gel compositions ensure the adsorption of
the ophthalmic drug on the mucous membrane of the eye or the like. Accordingly, Kogyo
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