Appeal No. 97-1843 Application 08/092,574 (10) Godtfredsen also discloses that fusidic acid and salts thereof may be mixed with a liquid or a solid pharmaceutical carrier, and may be used in any conventional form. Godtfredsen, column 6, lines 18-46. (11) Godtfredsen discloses that fusidic acid and salts thereof can be isolated in particulate form. Godtfredsen, column 2, lines 16-21; column 5, lines 41-46. Godtfredsen exemplifies a topical ointment in which the sodium salt of fusidic acid is used in particulate form. Godtfredsen, column 6, lines 56-74. In reviewing the above facts, the examiner should determine whether the subject matter recited in claims 6 through 9 as a whole would have been obvious at the time the invention was made to a person having ordinary skill in the art to which this subject matter pertains over the combined disclosures of Kogyo and Godtfredsen. In determining the patentability of claims 6 through 9, the examiner should also consider the facts presented in the Jensen Rule 132 Declaration. Patentability is determined on the totality of the record, by a preponderance of evidence with due consideration to persuasiveness of argument. See Oetiker, supra. “If the appellant comes forward with reasonable rebuttal, whether buttressed by experiment, prior art references, or argument, the entire merits of the matter are to be weighed.” Hedges, supra. IV. From a review of the application file, it is noted that priority under 35 U.S.C. § 119 is claimed to British patent application 8500310 filed Jan. 7, 1985. See the substitute 13Page: Previous 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 NextLast modified: November 3, 2007