Appeal No. 97-1843
Application 08/092,574
discloses that the gel compositions can produce sufficient medicinal effects without being
washed away by tears. Kogyo, page 2, lines 64 to 71.
(6) Kogyo further discloses that the gel compositions cause no discomfort to the
patient since they are free from oleophilic base ingredients. Kogyo, page 2,
lines 82-84.
(7) Kogyo discloses that when gel compositions that have a viscosity of from
1,000 to 10,000 cps are applied to the eye, the mucous membrane of the eye absorbs the
drug rapidly. Kogyo, page 2, lines 84-87.
(8) Kogyo discloses that when sustained efficacies are desired, a small amount of
sodium chloride can be added to the gel compositions to “delay” the breakdown of the gel
when the compositions are applied to the mucous membrane of the eye. Kogyo discloses
that although the addition of a small amount of sodium chloride to the aqueous solution of
the gel compositions coverts the gel to a liquid, greatly reducing its viscosity, the amount of
carboxyvinyl polymer can be increased to compensate for this reduction of viscosity.
Kogyo, page 2, lines 107-125.
(9) Godtfredsen discloses that fusidic acid and certain salts thereof are well known
antibiotics which are effective against a number of pathogenic microorganisms. See
Godtfredsen, Table 1.
12
Page: Previous 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Next
Last modified: November 3, 2007