Ex parte KOSLEY JR. et al. - Page 3




          Appeal No. 1997-2167                                                        
          Application 08/137,444                                                      
          appellants' invention.                                                      
               Claim 1. A compound of the formula                                     












               wherein                                                                
               R  is hydrogen, (C -C )alkylcarbonyl,1               1  I2                                                 
               (C -C )alkoxycarbonyl, aryl(C -C )alkylaminocarbonyl,1 I2                       1 I2                                      
               mono(C -C )alkylaminocarbonyl or                                       
                     1  18                                                            
               di(C -C )alkylaminocarbonyl;                                           
                   1 18                                                               
               R  is (C -C )alkylcarbonyloxy,2     1  I2                                                           
               aryl(C C )alkylcarbonyloxy, (C -C )alkoxycarbonyloxy,l-4                     1 12                                     
               arylcarbonyloxy, hydroxy,                                              
               (C -C )alkoxycarbonyl(C -C )alkoxy or                                  
                 1 6                 1  6                                             
               hydroxy(C -C )alkoxy;                                                  
                        l 10                                                          
               R  is hydrogen or halo; and pharmaceutically3                                                                     
               acce                                       ptable                      
               addi                                       tion salts;                 
               with                                       the proviso                 
               that                                       when R  is2                     
               hydr                                       oxy, R  and1                     
               R3                                         are not                     
               both                                       hydrogen or                 
               when                                       R  is2                          
               hydr                                       oxy and R3                  
               is                                         hydrogen, R1                

                                          3                                           





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