Ex parte KOSLEY JR. et al. - Page 4




          Appeal No. 1997-2167                                                        
          Application 08/137,444                                                      
          is not methylcarbonyl.                                                      
               Claim 2. The compound of Claim 1 wherein                               
                                                                                     
               R  is hydrogen, (C -C )alkylcarbonyl or (C -1               1  12                   1                            
               C )alkoxycarbonyl;                                                     
                12                                                                    
               R  is (C -C )alkylcarbonyloxy, arylcarbonyloxy,2     1  12                                                           
               (C -C )alkoxycarbonyloxy, hydroxy, (C -C )1 12                              1 6                               
               alkoxycarbonyl(C -C )alkoxy or hydroxy(C -C )1 6                   1  6                            
               alkoxy; and                                                            
               R  is hydrogen or halogen; with the proviso that when3                                                                     
                2           1        3                         2                    
               R  is hydroxy, R  and R  are not both hydrogen or R                    
                               3             1                                        
               is hydroxy and R  is hydrogen, R  is not                               
               methylcarbonyl.                                                        
                                                                                     
               Claim 48. A pharmaceutical composition which                           
               comprises a pharmaceutically acceptable carrier and                    
               an acetylcholinesterase inhibiting amount of the                       
               compound of Claim 1.                                                   
                                                                                     
                                                                                     
               Claim 49. A method of treating memory dysfunction                      
               characterized by decreased cholinergic function                        
               which comprises administering to a mammal an                           
               acetylcholine-sterase inhibiting amount of the                         
               compound of Claim 1.                                                   
               Claim 50. A method of                                                  
               treating memory dysfunction characterized by                           
               decreased cholinergic function with                                    
               6-O-demethylgalanthamine which comprises                               
               administering to a mammal an acetylcholinesterase                      
               inhibiting amount of the compound of Claim 2 when R3                   
               is hydrogen.                                                           
                                   RELATED APPEALS                                    
               On page 2, lines 1 through 9 of their brief, appellants                
          direct our attention to two, related appeals which, according               

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