Ex parte KOSLEY JR. et al. - Page 8




          Appeal No. 1997-2188                                                        
          Application 08/137,440                                                      
          appellants in their specification at page 8, line 24 through                
          page 10, line 18.  The compositions do not exclude any other                
          materials, including materials disclosed but not claimed and                
          materials neither disclosed nor even contemplated.                          
               Appellants' method claims are directed to two separate                 
          embodiments: one where memory dysfunction characterized by                  
          decreased cholinergic function is treated by administering the              
          compounds of claim 1 to a mammal in an amount effective to                  
          inhibit AChE; and, a second where memory dysfunction                        
          characterized by decreased cholinergic function is treated                  
          with 6-O-demethylgalanthamine, a known AChE inhibiting                      
          compound, by administering to a mammal in an amount sufficient              
          to inhibit AChE the compound of Claim 4.  Thus, both methods                
          are limited to treating memory dysfunction characterized by                 
          decreased cholinergic function.                                             
               The first method requires administering to a mammal with               
          memory dysfunction characterized by decreased cholinergic                   
          function an amount of the compound of claim 1 sufficient to                 
          inhibit the formation in the mammal of the enzyme AchE.  As a               
          "comprising" claim the first method does not exclude any other              
          step or ingredient, including steps or ingredients disclosed                
          but not claimed and even steps or ingredients neither                       
                                          8                                           





Page:  Previous  1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  Next 

Last modified: November 3, 2007