Appeal No. 96-2323 Application 08/116,555 For the above reasons, we hold that the process recited in appellants’ claim 1 would have been prima facie obvious to one of ordinary skill in the art over Fan. When a prima facie case of obviousness has been established, appellants have the burden of rebutting it by presenting objective evidence of non-obviousness. See In re Piasecki, 745 F.2d 1468, 1472, 223 USPQ 785, 788 (Fed. Cir. 1984); In re Keller, 642 F.2d 413, 425, 208 USPQ 871, 882 (CCPA 1981). A final determination regarding obviousness is then reached by starting anew and evaluating the rebuttal evidence along with the evidence upon which the conclusion of prima facie obviousness was based. See In re Rinehart, 531 F.2d 1048, 1052, 189 USPQ 143, 147 (CCPA 1976). Appellants have submitted a declaration by Kanda (filed July 7, 1994, paper no. 16) which shows the effect of the dissolved oxygen concentration of the water-in-oil emulsion before polymerization on the formation of agglomerates during polymerization. The declaration indicates (figure 1) that the amount of agglomerates rises sharply as the dissolved oxygen concentration is increased above 100 ppb, and Kanda states 5Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007