Appeal No. 1997-3813
Application No. 08/371,205
Claim 62 is reproduced below:
62. A packing for liquid chromatography
comprising porous calcium phosphate based granules
having open pores with an average pore size of from
0.01 to 20 Fm, said granules being composed of
crystalline particles with an average size of from 2
to 10Fm.
The subject matter on appeal relates to a packing for
liquid chromatography comprising the recited porous calcium
phosphate granules. According to the appellants, the claimed
packing provides high resolution and exhibits superior
resistance to pressure and dissolution. (Appeal brief, page
4.)
The examiner relies upon the following prior art
references as evidence of unpatentability:
Kirkland 3,505,785 Apr. 14,
1970
Takata et al. (Takata) 4,629,464 Dec. 16,
1986
T. Kawasaki, W. Kobayashi, K. Ikeda, S. Takahashi, and H.
Monma (Kawasaki), “High-performance liquid chromatography
using spherical aggregates of hydroxyapatite micro-crystals as
adsorbent,” 157 Eur. J. Biochem. 291-95 (1986).
advisory action of April 18, 1996 that the amendment will be
entered upon the filing of an appeal. (Paper 12.)
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