Appeal No. 1997-3813 Application No. 08/371,205 invention is described, either explicitly or inherently, in Takata. Hence, it is our determination that the examiner has not carried the initial burden of establishing a prima facie case of unpatentability. In re Oetiker, 977 F.2d 1443, 1445, 24 USPQ2d 1443, 1444 (Fed. Cir. 1992). Specifically, we find that Takata describes a sintered microporous hydroxyapatite body of an open pore structure having a porosity in the range from 20% to 50%, of which the micropores have a distribution of diameters in the range from 0.01 to 0.1 mm (10 to 100 Fm). (Column 2, lines 34-40.) The sintered microporous hydroxyapatite body is said to be useful as a filling in a bone cavity or as a prosthetic member. (Column 2, lines 29-33.) Takata further teaches: The microporous hydroxyapatite body as mentioned above can be prepared, taking the granular form suitable for filling use as a product form, for example, by admixing 100 parts by weight of a powdery hydroxyapatite having a particle size distribution as fine as possible or in the range from 0.1 to 10 Fm with from 25 to 100 parts by weight of a thermally decomposable powdery material having a particle diameter in the range from 0.01 to 0.1 mm [10 to 100 Fm] and granulating the powdery blend into granules having a particle diameter in the range from 0.1 to 3 mm [100 to 3000 Fm] by a known method, optionally, with admixture of a suitable binder such as an aqueous solution of polyvinyl alcohol followed by calcination and 4Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007