Ex parte ICHITSUKA et al, - Page 10




          Appeal No. 1997-3813                                                        
          Application No. 08/371,205                                                  


               application.  Broadly, particle sizes in the range                     
               of from 5 millimicrons to 1 micron may be employed.                    
               For convenience of preparing coatings of desired                       
               thickness, microparticles in the range of 25-1000 mF                   
               are preferred.  For many purposes, a relatively                        
               large pore size in the coating is desired to permit                    
               rapid diffusion of components in chromatographic                       
               processes.  Since the size of the microparticles                       
               determines the size of the pores, 100-1000 mF                          
               particles are preferred in cases where rapid                           
               diffusion is needed. [Underscoring added; col. 4,                      
               ll. 58-69.]                                                            
          Thus, in its broadest teaching, Kirkland does not describe the              
          use of microparticle sizes any larger than 1 micron.  Although              
          Kirkland uses the term “preferred” to describe the 100-1000 mF              
          particle size range for applications where rapid diffusion is               
          needed, this preferred range must be read in context with the               
          broadest workable range of “5 millimicrons to 1 micron.”                    
          Accordingly, even if Kawasaki is combined with Kirkland, one                
          of ordinary skill in the art would not have modified                        
          Kawasaki’s materials to contain crystalline particles having                
          sizes any larger than 1 micron.  This, of course, does not                  
          result in the invention recited in appealed claim 62.                       
          Therefore, the examiner has not established a prima facie case              
          of obviousness within the meaning of 35 U.S.C. § 103.                       



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