Ex Parte LIGLER et al - Page 12


                 Appeal No.  1999-1384                                                                                 
                 Application No.  08/583,912                                                                           
                        However, while both appellants and Kidwell recognize the result effective                      
                 variables, the object of appellants’ invention (appellants’ specification, bridging                   
                 paragraph, pages 3-4) is “to perform bioassays capable of detecting minute                            
                 quantities of an analyte in under one minute.”  In contrast, Kidwell prefers                          
                 (column 6, lines 26-28) an interaction time “between about one to about five                          
                 minutes, with two minutes being most preferred.”  Kidwell further discloses                           
                 (column 6, lines 32-33) that the longer the interaction time, the greater the                         
                 sensitivity.                                                                                          
                        The examiner is reminded that “[t]he consistent criterion for determination                    
                 of obviousness is whether the prior art would have suggested to one of ordinary                       
                 skill in the art that this process should be carried out and would have a                             
                 reasonable likelihood of success, viewed in the light of the prior art.”  In re Dow                   
                 Chemical Co. 837 F.2d 469, 473, 5 USPQ2d 1529, 1531 (Fed. Cir. 1988).  On                             
                 this record, the examiner has not provided, and we do not find, a suggestion in                       
                 the prior art, that the interaction times of one to about five minutes, as disclosed                  
                 by Kidwell, could be reduced, with a reasonable likelihood of success, to “about                      
                 0.1 sec through about 30 sec” as required by the claimed invention.  Instead, we                      
                 agree with appellants that Kidwell teaches away from analyte-membrane                                 
                 interaction times of about 0.1 through about 30 seconds.  On this record, there is                    
                 no suggestion to reduce the analyte-membrane interaction time below one                               
                 minute as taught by Kidwell.  Therefore, in our opinion, in contrast to the facts of                  
                 Boesch, the prior art relied on by the examiner would not have suggested the                          
                 kind of experimentation necessary to obtain appellants’ claimed invention.                            


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