SHIOKAWA et al. V. MAIENFISCH et al. - Page 40



                                                     iv.        Many of Shiokawa’s Assumptions Regarding the Guidance Provided                                                         
                                                                by the ‘146 Patent are Unsupported                                                                                     

                                Shiokawa attempts to lead us away from the plain language of the ‘146 patent with assumptions                                                          

                     that are based primarily upon unsupported declaration testimony.  For example,                                                                                    

                     Shiokawa repeatedly directs our attention to Dr. Pearson’s declaration testimony as support for their                                                             

                     assumptions regarding the guidance provided by the ‘146 patent.  Nothing in our rules or in our                                                                   

                     jurisprudence, however, requires us to credit the unsupported assertions of an expert witness.  Cf.                                                               

                     Rohm & Hass Co. v. Brotech Corp., 127 F.3d 1089, 1092, 44 USPQ2d 1459 (Fed. Cir. 1997).                                                                           

                                There are many instances where Shiokawa’s statements and Dr. Pearson’s declaration                                                                     

                     testimony appear unsupported by the evidence.  For instance, Shiokawa and Dr. Pearson fail to identify                                                            

                     sufficient evidentiary support for: (1) why one skilled in the art would be directed to classify the                                                              

                     compounds of Table 1 into their “core-heterocycle” groups; (2) how the ‘146 patent guides one skilled                                                             

                     in the art to classify the “core-heterocycles” of Table 1 into four groups with Group I being:                                                                    



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