VISSER et al v. HOFVANDER et al - Page 10




          Interference 103,579                                                        

                         A potato normally produces both amylose and                  
                    amylopectin with the amylose normally being present               
                    in an amount of 20 to 25%.  Both parties’ claimed                 
                    inventions are directed to improving the production               
                    of amylopectin in potatoes by the incorporation of                
                    antisense DNA matter into the potato plant genome.                
                         The Visser claimed invention is directed to the              
                    incorporation of the full length antisense potato                 
                    granule bound starch synthase (PGBSS) cDNA or gDNA                
                    into a potato plant, thereby inhibiting the production            
                    of amylose.  According to the evidence relied upon by             
                    Visser, the Visser modified potato plants produce                 
                    100% amylopectin and inhibit the production of any                
                    amylose.                                                          
                         The Hofvander claimed invention is directed to               
                    the incorporation of antisense fragments of the PGBSS             
                    gene into a potato plant to inhibit the production of             
                    amylose.  According to the evidence relied upon by                
                    Hofvander, his modified potato plants produce 91 to               
                    94% amylopectin, the remainder being amylose.                     
                         The difference in amylopectin production by using            
                    Visser’s modified potato plants rather than Hofvander’s           
                    modified potato plants is about 6%.  The Vissen [sic]             
                    evidence, however, does not show that the difference              
                    is unexpected.  While Visser’s potato plants and                  
                    Hofvander’s potato plants produce differing amounts of            
                    amylopectin, both sets of plants produce amylopectin in           
                    increased amounts over unmodified potato plants.  The             
                    APJ agrees with the Hofvander opposition that Visser’s            
                    motion fails to show that the difference in activity              
                    is unexpected thereby rendering the Visser claims                 
                    unobvious.  See, in general, In re Merck & Co., Inc.,             
                    800 F.2d 1091, 1099, 231 USPQ 375, 381 (Fed. Cir.                 
                    1986).                                                            
                    (2)  Visser’s Preliminary Motion 2 (VPM 2)(Paper                  
               No. 18) for judgment that Claims 1, 4, and 6 to 23 of                  
               Hofvander involved application, filed November 24, 1993,               
               are unpatentable under 35 U.S.C. § 102 over Hergersberg                

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