VISSER et al v. HOFVANDER et al - Page 98




          Interference 103,579                                                        
          homologous to the potato GBSS gene and functions to inhibit the             
          expression of the potato GBSS gene not only may be present in               
          Visser’s full length cDNA or genomic DNA sequence and Hofvander’s           
          2549 bp genomic DNA fragment and regulate GBSS expression in a              
          potato plant when inserted into its genome, it may also be                  
          present in Hergersberg’s 500/800 bp cDNA fragment and regulate              
          GBSS expression in a potato plant when inserted into its genome.            
          Nevertheless, Hofvander argues that expert testimonies presented            
          in this record by both parties portray Hergersberg’s publication            
          as being so fraught with error that persons having ordinary skill           
          in the art reasonably would not have relied upon Hergersberg’s              
          disclosure for DNA fragments capable of regulating potato GBSS              
          gene expression when inserted into the genome of a potato plant             
          in the antisense direction or for any other information (HB 45,             
          first para.).  More specifically, Hofvander states (VB 46, final            
          para.):                                                                     
               Hergersberg is not a reliable reference and would fail                 
               to disclose or suggest anything to a person skilled in                 
               the art.  As stated by Dr. Rask, Hergersberg is not                    
               reliable because “Hergersberg’s thesis is one of the                   
               most sloppy thesis I’ve ever seen and I’m astonished                   
               that it passed if it ever did” [Rask Testimony:                        
               HR 000140; page 77, lines 11-14] . . . .                               
               Notwithstanding the expert testimony of record that                    
          Hergersberg’s presentation was sloppy and showed Hergersberg’s              
          propensity for error, we find ample evidence of record that the             
          parties to this interference and their colleagues found                     
                                        -98-                                          





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