VISSER et al v. HOFVANDER et al - Page 92




          Interference 103,579                                                        
          claims designated as corresponding to the count is patentable               
          over Hergersberg’s teachings (VB 25, second full para.).                    
          However, Visser argues that the decision on preliminary motions             
          holding Hofvander’s claims designated as corresponding to the               
          count patentable over Hergersberg’s teachings is erroneous                  
          because the APJ was not fully apprized of Hergersberg’s teachings           
          (VB 21).  Visser argues (VB 21; footnote included in text):                 
               Although the APJ was advised that Hergersberg discloses                
               a GBSS cDNA fragment of about 275 base pairs, the APJ                  
               was not advised that another much longer fragment was                  
               used in Hergersberg’s antisense constructs.  Further,                  
               the APJ was not advised that Hergersberg used both of                  
               these fragments in a single antisense construct.                       
                    Several schematic diagrams comparing the sequences                
               used by each of Hofvander, Visser and Hergersberg, namely,             
               VDX2, HDX8  and VDX15 [n. “HDX8 and VDX15 are “corrected”              
               versions of VDX2.”], were presented during the motions                 
               period; however, none of them accurately depict the                    
               antisense fragments used by Hergersberg. . . . .                       
          Providing what Visser considers to be a clearer view of                     
          Hergersberg’s disclosure, Visser states (VB 22, second para.,               
          through VB 22-23, bridging para.)(footnote included in text):               
               Although [the APJ’s statement that “[t]he Hergersberg                  
               antisense sequences . . . are much smaller than those                  
               used by Hofvander” (Paper No. 74, p. 6)] . . . may be                  
               correct for the 275 base pair fragment when compared                   
               to SEQ ID No. 2 of Hofvander, clearly the 275 base pair                
               fragment is not much smaller than Hofvander fragment 1                 
               (SEQ ID No. 1) depicted as a 342 base pair fragment                    
               (“nr. 1") in HDX8 and VDX15.  In addition, it is now                   
               clear that fragment 1 of Hofvander overlaps with                       
               Hergersberg’s 275 base pair fragment by about 240                      
               base pairs (approximately 87%)(VDX29, HR139, 155-156).                 
                    In any event, there is a much larger fragment                     
                                        -92-                                          





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