Appeal No. 2001-0246 Application No. 08/921,103 is also prevented by the specific configuration of the inflow and exit tubes 15 and 16 (col. 4, lines 17-20). However, Appellants have not pointed to any specific teaching in Europe, nor have we found any, that limits the flow of the reference fluid to only the period after installing or replacing of the salt bridge. In this case, the reason to combine the references is derived from the nature of the subject matter involved, flowing the reference fluid from and to the junction into the same container where the reference liquid may be recirculated for further measurements of the sample liquid. As we discussed above, although Europe does not explicitly indicate that the reference fluid is recirculated through a container, we find that the Examiner has reasonably concluded that if the reference fluid in a free junction, where sample back diffusion may affect the purity of the reference fluid, is recirculated for economical reasons, there is an even stronger desire to do so in a constraint junction where the reference fluid is less likely to become contaminated (answer, page 9). The Examiner has relied on Europe for generally disclosing a constraint junction configuration while Hofmeier is relied on for suggesting the recirculating of the reference fluid even in a free junction in 10Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007