Ex Parte CHAN et al - Page 10




          Appeal No.  2001-0246                                                       
          Application No.  08/921,103                                                 

          is also prevented by the specific configuration of the inflow               
          and exit tubes 15 and 16 (col. 4, lines 17-20).  However,                   
          Appellants have not pointed to any specific teaching in Europe,             
          nor have we found any, that limits the flow of the reference                
          fluid to only the period after installing or replacing of the               
          salt bridge.                                                                
               In this case, the reason to combine the references is                  
          derived from the nature of the subject matter involved, flowing             
          the reference fluid from and to the junction into the same                  
          container where the reference liquid may be recirculated for                
          further measurements of the sample liquid.  As we discussed                 
          above, although Europe does not explicitly indicate that the                
          reference fluid is recirculated through a container, we find                
          that the Examiner has reasonably concluded that if the reference            
          fluid in a free junction, where sample back diffusion may affect            
          the purity of the reference fluid, is recirculated for                      
          economical reasons, there is an even stronger desire to do so in            
          a constraint junction where the reference fluid is less likely              
          to become contaminated (answer, page 9).  The Examiner has                  
          relied on Europe for generally disclosing a constraint junction             
          configuration while Hofmeier is relied on for suggesting the                
          recirculating of the reference fluid even in a free junction in             

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