Ex Parte GRANADOS et al - Page 13


                   Appeal No. 2002-2030                                                                 Page 13                       
                   Application No. 09/294,663                                                                                         

                   patentably distinct from the subject matter claimed in a commonly owned patent.”                                   
                   In re Berg, 140 F.3d 1428, 1431, 46 USPQ2d 1226, 1229 (Fed. Cir. 1998).                                            
                           Instant claims 3, 5, 7, and 10 compare to claims 1-3 and 6 of the ‘558                                     
                   patent as follows:                                                                                                 
                   Instant claim:                                   ‘558 patent claim:                                                
                   3.  A recombinant DNA sequence                   2.  An isolated polynucleotide encoding                           
                   comprising a DNA sequence that                   an invertebrate intestinal mucin, said                            
                   codes for an IIM protein, wherein a              polynucleotide comprising a nucleotide                            
                   nucleic acid sequence of said                    sequence selected from the group                                  
                   recombinant DNA sequence is selected             consisting of:                                                    
                   from the group consisting of:                            a) SEQ ID No. 1; and                                      
                           a) a cDNA sequence as shown                      b) SEQ ID No. 2.                                          
                   in SEQ ID No. 1; and                                                                                               
                           b) a cDNA sequence as shown                                                                                
                   in SEQ ID No. 2.                                                                                                   
                   5.  The recombinant DNA sequence of              1.  An isolated polynucleotide encoding                           
                   claim 3, wherein said IIM has an amino           an invertebrate intestinal mucin                                  
                   acid sequence selected from the group            comprising an amino acid sequence                                 
                   consisting of:                                   selected from the group consisting of:                            
                           a) SEQ ID No. 3; and                             a) SEQ ID No. 3; and                                      
                           b) SEQ ID No. 4.                                 b) SEQ ID No. 4.                                          
                   7.  A gene expression vector containing          3.  An expression vector comprising an                            
                   a recombinant DNA sequence                       expression control sequence                                       
                   encoding a Trichoplusia ni IIM protein           operatively linked to the polynucleotide                          
                   sequence.                                        of claim 1 or claim 2.                                            
                   10.  The expression vector of claim 7,           6.  The expression vector of claim 3,                             
                   wherein said expression vector is a              wherein the expression vector is a                                
                   recombinant plasmid adapted for                  plant expression vector.                                          
                   insertion into and transformation of a                                                                             
                   plant.                                                                                                             

                           Thus, claims 1 and 2 of the ‘558 patent are generic to instant claims 3 and                                
                   5.  That is, the ‘558 patent’s “isolated polynucleotide” is generic to DNA and                                     
                   RNA, either recombinant and nonrecombinant.  However, DNA is an obvious                                            
                   form of polynucleotide, in that it is one of only two available options; it is also the                            
                   form in which polynucleotides are stably found within living cells.  And                                           





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