Ex Parte GRANADOS et al - Page 11


                   Appeal No. 2002-2030                                                                 Page 11                       
                   Application No. 09/294,663                                                                                         

                   disclosure does little to reduce the experimentation needed to practice the                                        
                   claimed invention.  At best, it identifies several insect species that might contain                               
                   IIM-encoding genes similar in sequence to those of T. ni; the IIM-encoding genes                                   
                   from these species, therefore, might reasonably be expected to hybridize to a                                      
                   probe corresponding to part of the T. ni IIM cDNA.                                                                 
                           However, even if the evidence showed that IIM-encoding genes could be                                      
                   isolated from the eight other insect species shown to express 400 kD proteins                                      
                   that cross-react with antibody to T. ni IIM, without undue experimentation, such                                   
                   evidence would not show enablement of the full scope of claim 1.  Claim 1 is                                       
                   extremely broad; as the examiner pointed out, the category of invertebrates are                                    
                   not limited to insects, it also encompasses worms, mollusks such as snails and                                     
                   clams, and crustaceans such as lobsters.  Appellants have provided no evidence                                     
                   with respect to non-insect invertebrates.  Thus, the specification might, at best,                                 
                   provide a starting point for further research, but it does not provide a disclosure                                
                   that enables practice of the full scope of claim 1 without undue experimentation.                                  
                           Essentially, Appellants’ position is that, even though the specification                                   
                   provides no guidance regarding IIM-encoding genes in species other than T. ni,                                     
                   the claims are enabled because everything needed to practice the full scope of                                     
                   the claims was known in the art.  The Federal Circuit has cautioned against over-                                  
                   reliance on the rule, cited by Appellants here, that a patent need not teach, and                                  
                   preferably omits, what is well known in the art.  See Genentech Inc. v. Novo                                       
                   Nordisk A/S, 108 F.3d 1361, 1366, 42 USPQ2d 1001, 1005 (Fed. Cir. 1997):                                           
                   “[T]hat general, oft-repeated statement is merely a rule of supplementation, not a                                 





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