Ex Parte STEWART et al - Page 4



                 Appeal No. 2003-1417                                                         Page 4                   
                 Application No. 09/298,404                                                                            

                 1.  Double patenting                                                                                  
                        The examiner rejected claims 60-73 and 76 under the judicially created                         
                 doctrine of obviousness-type double patenting, based on claims 30-39 and 44 of                        
                 U.S. Patent 6,326,482.1                                                                               
                        Appellants, “[w]ithout necessarily agreeing with the propriety of the                          
                 outstanding rejection,” Appeal Brief, page 14, have not disputed its merits and                       
                 have agreed to file a terminal disclaimer to overcome it.  See id.  Since                             
                 Appellants has not argued that the rejection is improper, we affirm it.                               
                 2.  Anticipation                                                                                      
                        The examiner rejected claims 60-66, 68, 69, and 71-73 as anticipated by                        
                 Frackelton, based on the following reasoning:  “Nsp1, Nsp2 and Nsp3 . . . contain                     
                 phosphotyrosyl residues.  The monoclonal antibodies of [Frackelton] have affinity                     
                 for molecules containing o-phosphotyrosine residues, hence these antibodies                           
                 would unequivocally bind to polypeptides comprising the amino acid sequences                          
                 of SEQ ID NO:1-3.”  Examiner’s Answer, page 4.                                                        
                        Appellants agree with the examiner that the antibodies disclosed by                            
                 Frackelton would be expected to bind to Nsp1, Nsp2, and Nsp3, because they                            
                 would be expected to “bind to any phosphotyrosyl-containing polypeptide.”                             





                                                                                                                       
                 1 The ‘482 patent has only twenty-one claims; presumably, the examiner intended to reject the         
                 instant claims over the patented claims corresponding to application claims 30-39 and 44.             





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