Ex Parte STEWART et al - Page 5



                 Appeal No. 2003-1417                                                         Page 5                   
                 Application No. 09/298,404                                                                            

                        Appeal Brief, pages 5-6.  Appellants point out, however, that the instant                      
                 claims are directed to antibodies that “specifically bind” to one of Nsp1, Nsp2,                      
                 Nsp3.  Appellants construe this limitation to mean that “the presently claimed                        
                 antibodies . . . bind to polypeptides comprising the amino acid sequences of SEQ                      
                 ID NO:1, 3, or 5 and not substantially to any other polypeptides.”  Id. (emphasis                     
                 in original).                                                                                         
                        The examiner does not dispute this interpretation of the claims.  See the                      
                 Examiner’s Answer, page 9:  “The record reflects that the Examiner concurred                          
                 with Appellants’ definition of ‘specifically binds’. . . .  The term was defined as the               
                 binding of an antibody to a particular polypeptide and the antibody binds to that                     
                 particular polypeptide but does not substantially bind to any other polypeptide.”                     
                        “Under 35 U.S.C. § 102, every limitation of a claim must identically appear                    
                 in a single prior art reference for it to anticipate the claim.”  Gechter v. Davidson,                
                 116 F.3d 1454, 1457, 43 USPQ2d 1030, 1032 (Fed. Cir. 1997).  When                                     
                 construing claim language, “every limitation positively recited in a claim must be                    
                 given effect in order to determine what subject matter that claim defines.”  In re                    
                 Wilder, 429 F.2d 447, 450, 166 USPQ 545, 548 (CCPA 1970).                                             
                        Here, the examiner and Appellants agree that the claims are limited to                         
                 antibodies that “specifically” bind to Nsp1 (claim 60), Nsp2 (claim 61), or Nsp3                      
                 (claim 62), and they agree on the interpretation of that limitation:  the antibodies                  
                 bind to the recited polypeptide “and not substantially to any other polypeptides.”                    
                 Appeal Brief, page 6; see also Examiner’s Answer, page 9.                                             






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