Ex Parte STEWART et al - Page 7



                 Appeal No. 2003-1417                                                         Page 7                   
                 Application No. 09/298,404                                                                            

                 requires binding to the specified polypeptide without substantial binding to any                      
                 other polypeptide.  Thus, any antibody that binds to each of Nsp1, Nsp2, and                          
                 Nsp3 is outside the scope of claims 60, 61, and 62.  The rejection for anticipation                   
                 is reversed.                                                                                          
                 3.  Obviousness                                                                                       
                        The examiner rejected most of the claims as obvious over the prior art.                        
                 Each of the obviousness rejections was based on the examiner’s position that                          
                 Frackelton disclosed antibodies meeting all the limitations of the independent                        
                 claims.  However, we have concluded that Frackelton does not disclose                                 
                 antibodies that specifically bind Nsp1, Nsp2, or Nsp3.  The examiner has pointed                      
                 to nothing in the secondary references that would meet this limitation of the                         
                 claims.  We therefore reverse the rejections based on 35 U.S.C. § 103.                                
                                                      Summary                                                          
                        The prior art relied on by the examiner does not teach antibodies that                         
                 specifically bind to SEQ ID NO:1, SEQ ID NO:3, or SEQ ID NO:5 (Nsp1, Nsp2, or                         
                 Nsp3, respectively).  We therefore reverse the rejections for anticipation and                        
                 obviousness.  However, we affirm the rejection for obviousness-type double                            
                 patenting.                                                                                            













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