Appeal No. 2003-2146 Page 3
Application No. 09/546,143
XI,
wherein R1 is an acyl residue of an aromatic carboxylic acid and R4 is
an amino protecting group.
The references relied upon by the examiner are:
Barbier et al. (Barbier) 5,583,222 Dec. 10, 1996
(102(e) date Jan. 4, 1995)
Adams et al. (Adams), “Total synthesis of balanol: a potent protein kinase C
inhibitor of fungal origin,” J. Chem. Soc. Perkin Trans. I, pp. 2355-62 (1975)
Krogsgaard-Larsen et al. (Krogsgaard-Larsen), “Inhibitors of GABA Uptake.
Syntheses and 1H NMR Spectroscopic Investigations of Guvacine, (3RS, 4SR)-
4-Hydroxypiperidine-3-carboxylic Acid, and Related Compounds,” Acta Chemica
Scandinavica B, Vol. 32, pp. 327-34 (1978)
L. G. Wade, Jr. (Wade), Organic Chemistry 103 and 115 (Prentice-Hall, Inc.,
1987)
GROUND OF REJECTION
Claims 12, 14, 15, 17, 19, 21, 23 and 25 stand rejected under 35 U.S.C.
§ 112, second paragraph, as being indefinite in the recitation of the phrase
“amino protecting group.”
Claims 12, 14, 15, 17, 19, 21, 23 and 25 stand rejected under 35 U.S.C.
§ 112, first paragraph, as based on a disclosure that fails to enable the full scope
of the claimed invention.
Claim 17 stands rejected under 35 U.S.C. § 102(b) as anticipated by
Krogsgaard-Larsen.
Claims 23 and 25 stand rejected under 35 U.S.C. § 102(b) as anticipated
by Adams.
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