Ex Parte Matzinger et al - Page 4


                 Appeal No.  2003-2146                                                         Page 4                  
                 Application No.  09/546,143                                                                           
                        Claim 25 stands rejected under 35 U.S.C. § 102(e) as anticipated by                            
                 Barbier.                                                                                              
                        Claims 25 and 26 stand rejected under 35 U.S.C. § 103 as being                                 
                 unpatentable over Barbier.                                                                            
                        We reverse.                                                                                    
                                                    DISCUSSION                                                         
                 THE REJECTION UNDER 35 U.S.C. § 112, SECOND PARAGRAPH:                                                
                        The claims are directed to a compound selected from the group consisting                       
                 of compounds of a specified formula wherein one of the substituents, R4, set                          
                 forth in the specified formula is an amino-protecting group.  According to the                        
                 examiner (Answer, page 4), the “claims recite the limitation of ‘amino protecting                     
                 group’ which has no description in the specification other than ‘tert.-                               
                 butoxycarbonyl’ as a sole representative of said group.  Thus, one skilled in the                     
                 art cannot ascertain what other groups can be considered as an                                        
                 ‘amino[-]protecting group’.”  We note, however, while the examiner asserts (id.)                      
                 that the specification describes “tert.-butoxycarbonyl” as a sole representative of                   
                 an “amino-protecting group,” the examiner later finds (Answer, bridging sentence,                     
                 pages 4-5), the specification provides an enabling description of tert-butyl ester,                   
                 tert-butyl carboxylate, and tert-butoxycarbonyl as amino-protecting groups within                     
                 the scope of R4 as set forth in appellants’ claimed invention.                                        
                        For their part, appellants assert (Brief, page 4), “[t]he term ‘amino-                         
                 protecting group’, as used in the rejected claims, is well-known in the art to which                  
                 this invention belongs, organic synthesis.”  In support of this assertion appellants                  







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