WANG et al vs IMLER et al - Page 16




                Interference No. 105,136                                                                Paper 62                         
                Wang v. Imler                                                                           Page 16                          
                judgment against Wang as to priority. 37 CFR § 1.652.9                                                                   
                                                    Rule 659 recommendation                                                              
                        37 CFR § 1.659(a) states the following:                                                                          
                                Should the Board have knowledge of any ground for rejecting any                                          
                        application claim not involved in the judgment of the interference, it may                                       
                        include in its decision a recommended rejection of the claim.  Upon                                              
                        resumption of ex parte prosecution of the application, the examiner shall                                        
                        be bound by the recommendation and shall enter and maintain the                                                  
                        recommended rejection unless an amendment or showing of facts not                                                
                        previously of record is filed which, in the opinion of the examiner,                                             
                        overcomes the recommended rejection.                                                                             

                        In view of prior art that was submitted by Wang in its preliminary motion 1                                      
                (copies attached) and in accordance with 37 CFR § 1.659(a) the following rejection is                                    
                recommended:                                                                                                             


                        Claims 66 and 67 of Imler's '143 application (FF 34) are rejected under 35 USC                                   
                § 103(a) as being obvious in view of Berkner II (FF 35 (b)) and Bridge II (FF 35(d)).                                    
                        Berkner II describes the use of adenoviruses as expression vectors.  Berkner II                                  
                states that "[g]eneration of helper-independent Ad recombinants can be accomplished                                      
                by insertion of heterologous sequences into several different regions of the Ad                                          
                genome....Substitution of the E1 or E4 regions produces conditional recombinants                                         
                which can be propagated in complementing cell lines".  (FF 42).  Berkner II describes                                    


                        9       As noted in the order entered 23 December 2003, "[n]o order to show                                      
                cause is necessary in this situation because the positions of the parties are clear                                      
                enough" (Paper 37 at 1-2).                                                                                               
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