Appeal No. 2006-0103 Page 4 Application No. 10/172,892 “form-in-place gasket.” As defined by the specification (page 8), a form-in-place gasket is one that is formed by depositing a fluid gasket material on a surface and allowing the gasket material to cure (pages 17-18). Claim 10 adds the limitation that the target solution is placed into a well on either the substrate or cover, and then the other plate is placed over the well to form the assay chamber. Claim 17 is similar to claim 1 but adds the express product-by-process limitation that “the form-in-place gasket [is] formed by a process comprising depositing a fluid gasket material on one or more of the substrate and the cover and curing the fluid gasket material.” 2. Anticipation by Chen The examiner rejected claims 1-13, 16, and 17 under 35 U.S.C. § 102(e) as anticipated by Chen.1 Chen discloses a “hybridization assembly compris[ing] a reaction chamber (or hybridization chamber) to confine and allow interaction or binding of a target liquid to an array of probes deposited on an inner surface of the reaction chamber. The hybridization assembly may comprise a substrate slide, a gasket layer and/or a middle slide, and a cover slip.” Page 1, paragraph [0156]. Chen teaches that the “gasket layer may be attached to the surface of the middle slide that contacts the substrate to serve as a seal. . . . This gasket layer should ideally be made of softer and hydrophobic material such as silicone rubber, polytetrafluoroethylene, Teflon®, or polydimethylsiloxane 1 Chen et al., U.S. Publication No. 2003/0087292, published May 8, 2003 (application filed Oct. 4, 2002 and claiming priority to Oct. 4, 2001). The examiner also rejected claims 1-13, 16, and 17 as anticipated by Sandstrom (U.S. Patent 6,545,758, issued April 8, 2003 on an application filed Oct. 5, 2000). Since we conclude that these claims are anticipated by Chen, we need not reach the rejection based on Sandstrom.Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007